The Red Sox beat the Mariners 2-0 in their series opener in Seattle.
Roman Anthony opened the scoring with his first career home run and Abraham Toro drove in the club's other run.
Lucas Giolito did not allow a run and struck out 10 in six inning of work to earn the victory.
Aroldis Chapman locked down his 13th save of the season.
Boston has won six in a row and eight of its last nine to improve to 38-and-36.
Seattle had just four hits in the contest and went one-for-nine with runners in scoring position.
Logan Gilbert got the loss after he allowed a pair of runs in five innings on the mound.
The Mariners are now 36-and-34.
(Photo by Alika Jenner/Getty Images)
Photo: Alika Jenner / Getty Images Sport / Getty Images